Bacteria is the most commonly used probiotics with many species like Lactobacillus, Streptococcus, Enterococcus, Bacillus, Clostridium, Bifidobacterium, and many more. Certain types of fungal species are used as probiotics which include both yeasts and molds. Bacterial probiotics are also known to be effective in poultry, pigs, and calves with underdeveloped rumen. However, fungal probiotics are effective in ruminants.
Some microorganisms like lactic acid bacteria, Bacillus sp., Clostridium sp. And E.coli have been used as animal probiotics for quite some time and they are well suited for their major purpose benefiting the inside of the animal digestive tract. The main advantage of these microbial probiotic Bacillus is their similar characteristics to the bacteria in the animal digestive tract, allowing them to form a cluster in the intestinal mucosa and eliminate harmful bacteria. Probiotics can also inhibit the production of toxins like indole, skatole, phenol, amines, and ammonia. They can even help promote the formation of the immune system like IgA, IgG, and IgM to boost immunity and improve nutrient utilization by promoting sugar absorption and the production of enzymes.
The benefits of consuming Bacillus probiotics
The Probiotic CMO Bacillus benefits in microorganisms must be examined from a variety of perspectives. Some bacterial probiotics other than Bacillus must be able to reach the digestive tract and be able to survive as well as multiply. Hence most of the probiotics must have the capacity to resist bile salts and acid.
Bacillus only multiplies to a small degree when they reach the small intestine, but Bacillus can multiply extensively when they reach the large intestine. According to some recent reports, it is indicated that Bacillus can grow as a facultative anaerobe which is capable of living a sporulation-germination-sporulation cycle in the gastrointestinal tract. The multiplication of Bacillus spores revealed that the small intestine’s proliferation is difficult despite the presence of rich nutrients.
Enzymes & Metabolites produced by Bacillus
Bacillus is best known for producing various digestive enzymes, including amylase, protease, phosphatase, phytase, glucanase, isomerase, and fiber-digestive enzymes. The level of enzyme produced is very low during the process of Submerged Fermentation which is used to produce probiotics that can stimulate enzyme production.
Probiotic Bacillus also produces various types of amino acids, nucleic acids, peptides, oligomers, and biosurfactants when they are cultured as a production medium for grain-based ingredients like rice bran and soybeans.
Research has shown that probiotic strain can help in:
- Fighting against Irritable Bowel Syndrome (IBS)
- Advert conditions in Crohn’s Disease
- Prevent diarrhea by associating with antibiotics
- It can also help in flatness, bloating, and gas
- It can improve hyperlipidemia
- Bacillus probiotics can help in preventing or treating autoimmune diseases like osteoarthritis, rheumatoid arthritis, etc.
- It also helps the body in coping with viral attacks like influenza
- It can help to enhance athletic performance by reducing muscle damage markers, increase recovery after damage in exercising.
- It has also been shown to be an alternative for women who are suffering from non-specific vaginosis
The strain of Probiotic CMO Bacillus clausii was noticed as a novel species upon its ability to hydrolyze casein, reduce nitrate, and its ability to grow at 50°C. Many further tests also showed that Bacillus clausii can use multiple sources of carbon, including L-aribose, galactose, dulcitol, xylitol, sorbitol, mannose, N-acetylglucosamine, methyl a-D-mannoside, D-tagose, and 2-ketogluconate.