What is a preimplantation genetic diagnosis? Pre-implantation genetic diagnosis (PGD) is a technique for analyzing embryos to differentiate those who are carriers of a genetic defect from those who are genetically normal. The objective of this technique is to avoid the birth of children with chromosomal abnormalities since embryos diagnosed as abnormal are discarded for transfer. This increases the probability of embryo implantation and the probability of successful in vitro fertilization (IVF) treatment. PGD is a method that makes it possible to eliminate the probability of transmission of genetic diseases from parents to children. PGD detects point mutations in embryos that cause serious genetic diseases. PGD is indicated as a complement to the IVF-ICSI process in the following situations: – When one or both partners are carriers of a disease or genetic abnormality. – When one or both members of the couple have an alteration in the number of chromosomes. –
Repeated implantation failure. –
Repeated miscarriages. – Advanced maternal age. The age of the mother increases the probability of genetic abnormalities within the embryo. This percentage is higher in women over 40. – Family history of the disease or genetic alteration. When people plan to do PGD when trying for pregnancy, they will achieve these benefits: – Avoids the transfer of embryos with chromosomal alterations, therefore allows only the transfer of healthy embryos. – Increases the rate of implantation. – Increased pregnancy rate. – Reduced abortion rate. – Decreases the risk of children born with chromosomal syndromes known as Huntington’s disease and muscular dystrophy. If you’re planning to undergo in vitro fertilization (IVF). Preimplantation Genetic Diagnosis (PGD) testing is performed before the implantation so that the embryos can be carefully selected to prevent genetic conditions being passed on to the child. And improve a woman’s chances of giving birth to a healthy baby.
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